Skip to product information
1 of 8

A Defiance Retinol Renewal Gel

A Defiance Retinol Renewal Gel

4.3
Rated 4.3 out of 5 stars
12 Reviews

Anti-Aging Overnight Renewal Gel

Regular price $49.00 $49.00 $44.10
Regular price $49.00 Sale price $49.00
Sale Sold out
A nighttime renewal gel that’s formulated to work during skin’s natural repair phase. This multi-tasking retinol-rich treatment helps regenerate skin overnight to reveal a brighter, smoother complexion.

How it Works

Apply a thin layer to skin after cleansing. If necessary, a moisturizer can be layered on top.

Product Benefits

  • Supports a brighter, smoother complexion
  • Works overnight to help rejuvenate skin

Key Ingredients

Retinol: Helps boost collagen production to diminish signs of aging and improve elasticity.


Retinyl Palmitate: Helps stimulate cell turnover to improve skin’s structure, firmness, and clarity.

Full Ingredient List

Aqua (Water), Glycerin, Glycolic Acid, Sodium Hydroxide, Lactic Acid, Cyclopentasiloxane, Carbomer, Panthenol, Mandelic Acid, Vaccinium Myrtillus Fruit Extract, Saccharum Officinarum (Sugar Cane) Extract, Citrus Limon (Lemon) Fruit Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Retinol, Retinyl Palmitate, Helianthus Annuus (Sunflower) Seed Oil, Acer Saccharum (Sugar Maple) Extract, Zea Mays (Corn) Germoil, Tocopherol, Beta-carotene, Lecithin, Prunus Persica (Peach) Fruit Extract, Xanthan Gum, Dimethiconol, Caprylic/capric Glycerides, Acrylates/c10-30 Alkyl Acrylate Crosspolymer, Dipotassium Glycyrrhizate, Disodium Edta, Polymethyl Methacrylate, Bht, Triethanolamine, Tricaprylin, Alcohol, Ethylhexylglycerin, Parfum (Fragrance), Phenoxyethanol.

View full details
  • Icon indicating Serious Skincare products are cruelty-free

    Cruelty-Free

  • Icon representing Serious Skincare for sensitive skin

    Sensitive Skin Approved

  • Icon representing Serious Skincare recommended by dermatologists

    Board-Certified Dermatologist Approved

4.3
Rated 4.3 out of 5 stars
Based on 12 reviews
Total 5 star reviews: 9 Total 4 star reviews: 1 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 2
83%would recommend this product
12 reviews
  • DC
    Diane C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    All time favorite

    This is one of my favorite products. It makes my skin look and feel great.

  • SA
    Sandra A.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Excellent product

    Use overnight face is glowing in the morning. Been using serious skincare products for almost 20 years. I'm 57 and no wrinkles. Love their products.

  • LL
    Lourdes L.
    Verified Buyer
    I do not recommend this product
    Rated 1 out of 5 stars
    2 weeks ago
    Bad customer service

    No exp. Date. How do I know this is good? Do you documentation about the lot# when it was manufactured?

  • LP
    Laura P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    A defiance retinol renewal gel

    My face feels smoother in the morning

  • KP
    Kerri P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Love this

    I love this evening gel with retinol, I’ve used for two weeks and already see a difference. I will keep using

Reviews LoadedReviews Added

Frequently Asked Questions

Do you offer any product guarantee?

All of our products are backed by a 30-day money back guarantee. If you are unsatisfied with your product for any reason, simply contact customer care to redeem your refund.

How long will it take to get my order?

All orders are typically processed within 24 hours of being received. You can expect your order to be delivered to your door within 5 working days.

Is it possible to track my order?

Absolutely! Once your order is processed and shipped from our distribution center, you will receive a tracking number via email. This will allow you to track your order all the way to your doorstep.

Where do you currently ship?

We have distribution centers throughout the U.S. so we ship to all 50 states. Our shipping partners are reliable and always take care of our customers.

How can I get in touch with customer support?

Our customer care team is available to answer your questions and offer order support. You can get in touch with us by emailing support@seriousskincare.com or calling +1-800-540-8662.

All returns should be sent to:

Serious Skincare Returns

ATTN: Blue Logistics

8825 Boggy Creek Rd

Orlando, FL 32824