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  • A tube of 'A Defiance 4 Million IU A Cream' by Serious Skincare, designed for skin care and anti-aging. Retinol.
  • Skincare cream tube with text on a gray background. A tube of A Defiance 4 million iu cream. Serious Skincare. Retinol.
  • 4 Million IU ingredients. Vitamin A. Retinyl. Retinol.
  • 4 million IU - A Defy. Vitamin A. Retinol.
  • Skincare cream tube with green leaves on a light marble background
  • Before and after comparison of skin texture with text indicating time elapsed.
  • Retinol eye cream with microencapsulated retinol and retinyl palmitate to visibly smooth fine lines, wrinkles and dark circles.
  • Before and after comparison of skin texture on a person's shoulder, labeled 'Before' and 'After 30 days'.
  • Retinol eye cream with microencapsulated retinol and retinyl palmitate to visibly smooth fine lines, wrinkles and dark circles.
  • Retinol eye cream with microencapsulated retinol and retinyl palmitate to visibly smooth fine lines, wrinkles and dark circles.
  • Before and after comparison of skin texture on a white background
  • Retinol eye cream with microencapsulated retinol and retinyl palmitate to visibly smooth fine lines, wrinkles and dark circles.
  • Before and after comparison of skin texture on a white background
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4 Million IU A Cream

4.8
Rated 4.8 out of 5 stars
29 Reviews

Time-Release, Microencapsulated Retinol Cream

$44.00 $44.00 $39.60
$44.00 $44.00
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Shipping calculated at checkout.

4 Million IU. Maximum Vitamin A Renewal.

Turn up the power of your nighttime skincare routine with Serious Skincare A Cream 4 Million IU, an intensive retinol moisturizer created to renew, smooth and deeply hydrate aging skin.

This advanced formula delivers an impressive 4 Million International Units (IU) of Retinyl Palmitate per tube, combined with a second effective form of Vitamin A for comprehensive age-defying care. Time-released, microencapsulated retinol technology provides a controlled delivery of Vitamin A to help promote healthy-looking skin renewal while targeting the appearance of fine lines, wrinkles, uneven texture and visible sun damage.

But A Cream is more than a retinol treatment. The rich formula surrounds skin with moisturizers, minerals and antioxidants, helping replenish essential hydration and leaving the complexion feeling soft, supple and beautifully conditioned.

With consistent use, skin appears smoother, firmer, more refined and visibly renewed with a fresh, youthful-looking glow.

WHY YOU’LL LOVE IT

  • 4 Million IU Retinyl Palmitate — Delivers an intensive dose of Vitamin A in every tube
  • Two Forms of Vitamin A — Provides comprehensive age-defying skincare benefits
  • Time-Released Retinol — Microencapsulated technology provides controlled delivery
  • Smooths Lines + Wrinkles — Helps soften the appearance of visible signs of aging
  • Renews Skin Texture — Promotes a smoother, more refined-looking complexion
  • Deeply Moisturizes — Helps replenish dry, moisture-depleted skin
  • Antioxidant-Rich Care — Helps defend against environmental stressors
  • Restores Radiance — Reveals softer, smoother and more youthful-looking skin

Serious Vitamin A. Serious moisture. Serious renewal.

How it Works

Apply to a freshly cleansed, dry face or on top of a serum. Gently massage into skin, using caution around eyes.

Product Benefits

  • 4 Million IU Retinyl Palmitate — Delivers an intensive dose of Vitamin A in every tube
  • Two Forms of Vitamin A — Provides comprehensive age-defying skincare benefits
  • Time-Released Retinol — Microencapsulated technology provides controlled delivery
  • Smooths Lines + Wrinkles — Helps soften the appearance of visible signs of aging
  • Renews Skin Texture — Promotes a smoother, more refined-looking complexion
  • Deeply Moisturizes — Helps replenish dry, moisture-depleted skin
  • Antioxidant-Rich Care — Helps defend against environmental stressors
  • Restores Radiance — Reveals softer, smoother and more youthful-looking skin

Key Ingredients

Retinol: Helps boost collagen production to diminish signs of aging and improve elasticity.
Retinyl Palmitate: Helps stimulate cell turnover to improve skin’s firmness, and clarity.

Full Ingredient List

Water, Isopropyl Myristate, Isocetyl Stearate, Petrolatum, Cetyl Alcohol, Retinyl Palmitate, Glycerin, Ethylhexyl Methoxycinnamate, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Phenyl Trimethicone, Dimethicone, Laneth-16, Ceteth-16, Oleth-16, Steareth-16, Retinol, Vitis Vinifera (Grape) Seed Extract, Camellia Oleifera (Green Tea) Leaf Extract, Geranium Maculatum Oil, Citrus Aurantium; Amara (Bitter Orange) Oil, Cananga Odorata Flower (Ylang Ylang) Oil, Citrus Medica Limonum (Lemon) Oil, Citrus Grandis (Grapefruit) Fruit Oil, Aniba Rosaeodora (Rosewood) Wood Oil, Citral Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Santalum Album (Sandalwood) Oil, Jasminum Officinale (Jasmine) Oil, Jasminum Officinale (jasmine) Flower Extract, Lecithin, Sorbitol, Xanthan Gum, Annatto, Beta Carotene, Zea Mays (Corn) Oil, Disodium EDTA, Propylene Glycol, Diazolidinyl Urea, Phenoxyethanol, Methylparaben, Butylparaben, Ethylparaben, Propylparaben, Isobutylparaben, Fragrance.

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  • Cruelty-Free

  • Sensitive Skin Approved

  • Board-Certified Dermatologist Approved
4.8
Rated 4.8 out of 5 stars
Based on 29 reviews
Total 5 star reviews: 26
Total 4 star reviews: 2
Total 3 star reviews: 0
Total 2 star reviews: 0
Total 1 star reviews: 1
93%would recommend this product
Write a Review (Opens in a new window)
29 reviews
  • E
    Elise
    I recommend this product
    Rated 5 out of 5 stars
    8 months ago
    5 Stars

    Fantastic product! I love it😊

    Was this helpful?
  • D
    Deborah
    I recommend this product
    Rated 5 out of 5 stars
    1 year ago
    Love it

    I’m almost out and I need to get some more. I’m 63 years old and my face needs a lot of help, since I bought this. I have noticed a big change in my face.. I only use it once in the morning. I don’t wear makeup. For some reason, it’s like it puts a protection over my face, especially from the sun.. my over all complexion looks a whole lot, nicer and smooth.

    Was this helpful?
  • MS
    Mary S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 years ago
    Excellent

    I love these products

    Was this helpful?
  • C
    Cathy
    Verified Reviewer
    I do not recommend this product
    Rated 1 out of 5 stars
    2 years ago
    NOT CLEAN BEAUTY!!

    I would absolutely LOVE to start using this again but please take out the parabens! I used this for many, many years until parabens came to light and we are urged to use clean beauty products because of the rise in cancers. PLEASE, make this a clean beauty product and take out the parabens. It has such a nice texture, has some good ingredients, my skin drinks it in, it leaves my skin dewey and I've searched for a few years for something similar in a cream and I just can't find one! If all the other company's can make clean beauty products so can you Jennifer! PLEASE, PLEASE CONSIDER

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  • JH
    Janie H.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    2 years ago
    A Defiance 4 million iu

    I should have bought the c restore that I usually use and like, I used to use the a cream for many years, but not find it irritating to my skin. Waiting on c restore to go on sale, and will purchase it, hoping when on QVC it will have a special.

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Frequently Asked Questions

Do you offer any product guarantee?

Shop with confidence. Every Serious Skincare product is backed by our 30-Day Money-Back Guarantee. If you’re not completely satisfied with your purchase, simply contact our Customer Care team within 30 days and we’ll be happy to assist you with your return and refund.

How long will it take to get my order?

We work quickly to get your Serious Skincare favorites on their way! Most orders are processed within 1 business dayand typically arrive within 3–5 business days after shipping. Once your order is on its way, we’ll email you tracking information so you can follow it right to your door.
We’re excited to bring Serious Skincare to our Canadian customers! Most orders are processed within 1 business day and typically arrive within 7–14 business days after shipping. Delivery times may vary depending on your location and customs processing. Once your order is on its way, you’ll receive a shipping confirmation email with tracking information so you can follow your package right to your door.

Is it possible to track my order?

Absolutely! Once your order has been processed and shipped from our distribution center, you’ll receive ashipping confirmation email with your tracking informationso you can follow your order’s journey right to your doorstep.

Where do you currently ship?

We ship throughout theUnited States and Canada, making it easy to get your Serious Skincare favorites delivered right to your door. Our trusted shipping partners help ensure your order is handled with care from our distribution center to you.

How can I get in touch with customer support?

We're Here to Help

Our Customer Care team is happy to answer your questions and assist with your order.

Email: support@seriousskincare.com
Phone: 1-800-540-8662

Returns

Please send all returns to:

Serious Skincare Returns
ATTN: Blue Logistics
8825 Boggy Creek Rd
Orlando, FL 32824